Totally informal poll time, yayy!
1) Megacorporations (And, if so, which one needs more air time?)
2) Dragons (And, if so, which one needs more face time?)
3) Crimincal Syndicates (And if so, which one? Tongs, Mafia, Vory, etc.)
4) Government Action (War, corruption, whatever aspect you can think of.)
5) Racists! (Get yo' hate on!)
6) Bugs!
7) Horrors!
Shedim!
9) Other Spirits!
10) AIs
11) Technomancers
12) Other (Please define)
There's probably something really, really obvious that I've forgotten, but, hey.