I'd spout something about a horde of maniacs swinging deadly lutefisks and slaughtering countless thousands - but having lived in Minnesota from birth to present (I was actually born fairly close to Duluth) and never having even
seen a lutefisk, I wouldn't want to overly-reinforce that stereotype. =P
But back on topic, looking at a timeline I found it says that in 2027:
-Parabiologicals appear in Northern Minnesota carrying new and dangerous virus strains.
Also in 2039:
-Alamos 20,000 attempts a mass murder spree in Duluth, Minnesota. Eleven members of the terrorist group are captured but escape the day before being turned over to state authorities.
So essentially the hardy Minnesotans were defeated by swine-flu and terrorists. It was only this combination that could stand a chance against us.
Source:
http://www.hoboes.com/pub/Role-Playing/Shadowrun/Timelines/timeline.htmlI think it might be from a previous edition or something, not sure if it is actually a legitimate timeline.