I've done two human martial artist builds. The adept had Prototype Transhuman like JoeNapalm's, heavily augmented, mostly with bioware. I also took Rapid Draw and Missile Mastery to complement it. Someone who needs no weapons - he can use his hands and feet in close, or pick up anything at hand to throw at greater range. The mundane human, by contrast, was better at tanking, equally good at damage, and slower but with better passive dodge. His main thing, though, was an Edge of 7 and the RIM quality.