Definitely wouldn't say that about bioware - at least not exactly. I can very easily see after 3 or 5 years the corporation sending a notice to those people with SupraThyroidMax 3.4 that it's been observed in long-term users that the modified Glucagon X it produces breaks down far more rapidly than standard, and that the corporation is recommending a modified-gene-therapy 'refinement package' (now for sale at a discount of 13.8%) which will extend the life of the SupraThyroidMax 3.4 by an estimated 18 months. Or, you know, you could upgrade to the SupraThyroidMega 2.2 (at a discount of 6.9%) and not concern yourself with it for 'at least' several years to come ...
And I disagree about EVO. The sort of thing you're describing, while it fits into EVO's 'transhuman' adventure, doesn't quite jive with the 'everyone is fine the way they are, and accepted' starting point that EVO has. What has been said about Smart Brain and their attitudes sounds more like a sort of Infection - which, in truth, sort of might point you towards the Ordo Maximus, especially if your players are into the whole gothic horror thing.
Have them discover a small 'research group' blood bank experimenting with infusing blood with HMHVV (the standard vampiric strain) to see if 'unassociated' infection - i.e. that which doesn't involve a vampire infecting/draining the target - is possible. They discover that the ringleader has ties to a political action group in the nation's capital ... and that, after further research, they discover has ties to the Ordo. And then have them start tracing Ordo influence to dozens of companies, through scores of Infected ...