No its not really worth it I don't think. At least on the hyper specialized average combat adept everyone is thinking about. Its to me its similar to taking a 20 point quality like a way because I'm paying 10 karma, then I pick up another 10 karma negative quality. It saves me the power point I've spent on my bio adept build, but I only get another 2 points of improved ability.
Is +2 to one of your dice pools worth it for 20 karma?
Only people with crazy karma who just wanna see how high they can get their dice pool should take this. Which is this qualities real plus side, your not limiting yourself. Your not lowering a point of essence to limit your potential, you still have room for a few positive qualities you can get at character creation.