I don't see any modifiers to casting while astrally perceiving, and when you start to run up the guy will stand up far enough to see you coming, so you will have LOS., go ahead and roll your spell.
Necro, where exactly is O'Connor running to? The fence? Into the lot towards the car or the door? what is the plan here? I may have over done the size of the street a little bit, but you are definitely going to be out in the open at the end of 27 m of straight running.
If anyone feels it is useful to do so, feel free to modify and repost the map to accomodate your movement.