How many Lonestar can you fit in an Ares Citymaster? Are they expected to fire through the armored windows (how many can do that?), or do they poor out like it's a clown car?
When you have multiple people using suppressive fire on the same area, do the people in that area suffer a cumulative penalty as they attempt to dodge each set of bullets?
Does the scatter on a grenade keep it from being shot into a truck to annihilate the passengers?
This is one of the reasons why I don't like 4e or 5e vehicle information - it's been severely culled of critical information. Going back to 3e, we find that the Citymaster has for seats 2 bucket and 5 benches - fitting one (non-troll) person in each bucket seat and two human-sized (three if you cram) on each bench seat. Figure 12 standard.
Firing ports, well, my group originally presumed that all passengers had a firing port handy - between 60 and 120 degrees of a firing arc, centered on the port. Other GMs could decide other things; SR4 and SR5 state that it has two firing ports for the passengers, so 2 passengers shooting.
SR3 also stated that for doors it had 2 standard (for the people up front, in the two bucket seats) and one double-sized rear-facing door - i.e. an assault door going out the back. One
can decide that this means that the five bench seats are set up to be two on either side and one back-to-back with the two bucket seats in the front, instead of all five facing front; this is only logical, considering the vehicle is supposed to be the cop's version of an APC, i.e. a SWAT (or HTRT) van. Pop open the back doors, and it's less like a clown car and more like ten guys with guns in your face.
As for the multiple-suppressive-fire thing ... good question. Dunno. Depending on firing angles and everything, as well as how cinematic I'm trying to play, I might either give them a penalty of the highest for that area (cinematic), or else just stack it up (realistic/lethal).
Firing a grenade into the just-opening back of a Citymaster is HIGHLY ENCOURAGED by shadowrunners everywhere. (Well, most of 'em.) Typically, the skill you have (and the successes you get) reduces the scatter of the grenade; once it's down to 0, it blows up right where you want it. And at that point, the people inside the highly-armored enclosed space are screaming to get out, due to the inevitable Chunky Salsa effect.