If I recall correctly, the weapon used against Sirrurg was developed as part of Operation: Maurauder, and is referred to as Blue-227. It was described as a biochemical weapon that would affect something in a dragon's blood and act as a blood thinner (or a blood thickener, I believe).
Black Mamba's fate is uncertain (though I think she's KIA due to the finality of her statement), but it definitely seems that Blue-227 had adverse affects on non-dragon metahumans if you believe her wording. To me, it sounds like the PAX compound from Serenity, in that it increases aggression in certain (maybe all, in the case of B227) subjects.