A person would be more likely to LOSE Magic/Resonance than anything else. The so-called 'Sybil Virus' is closely akin to PAB emulators, psychotropic IC, and BTL personafix chip use. They don't make you lose Magic/Resonance ... or rather, you don't lose it right away. It takes repeated high-level exposure to them for magic (and by inference, resonance) to get burned out, but it does happen - look at the main character in Critias' Neat, who'd been a BTL junkie who nearly burned his magic out of himself.
So getting your synapses rewritten? Won't screw with your magic or resonance instantly - but over time, it's going to cut the throat on both of them. What I think the entities that are the 'virus' don't understand/realize is that loading themselves into the meat makes them bound to the rules of the meat ...