As someone currently tinkering around in Chummer for this game, I'm using a lot of knowledge skills, but using ones that have possible application (Security Procedures for hacker types, Magical Threats for mages, etc.) rather than stuff like "Cheesy Action Trids" that might be on a BP character with 15-21 "free" points. Also, languages are always useful, though as Lethe said, it'd be nice to know the setting/themes to pare down some stuff (ie if the campaign isn't set in Seattle, some languages might come in and out of favor, especially French)
Also, good to know about the metatype pricing change.