Hahaha @ all of you. Sounds like I'll be in for some new insights into Shadowrun's system.

It's just so different! So it's hard for me to comprehend with my little playtime. Like Crash mentioned, characters start with almost all their defensive capabilities. Compare that to D&D where characters sometimes start with a whopping 4 hitpoints lol. But at level 15+ in D&D, characters are teleporting, stopping time, talking to gods, controlling minds, casting power word: stun/kill, raising armies of undead (or the living sometimes), etc. That's the part I had a hard time dealing with. Shadowrun's setting, being a dystopia, makes it clear from the get-go that the players are at a disadvantage. The Government is corrupt. The Corps are corrupt. You're just there to survive, because the whole world is there to control you. Like Crash also said, SR is supposed to be mainly about roleplaying.
One of my players is creating a face, a FACE! I was worried they'd all be mages or street samurai, but someone's actually focusing on a roleplaying-based build!

He did double-check with me cause he was actually worried that a character who wasn't combat-focused wouldn't be as helpful or would die too soon. I haven't DMed for this group in about 4 years, and they've spent the last 18 months going through the "World's Largest Dungeon" (which is heavy on fighting and not much else), so I assured him that a face would be just as useful as any combat-oriented character.
I do think I'll research cyberpsychosis now though lol, thanks for the heads up!

I do have another question, if y'all don't mind. I decided to run Parliament of Thieves instead of Mission Briefing, since it's SR4. The adventure has the party making two border crossings (Pueblo/CAS and CAS/UCAS) but I looked at a map of North America:
http://seventh-legion.net/images/0/06/Map_of_North_America_Circa_2070.pngWhat's to keep the party from just making one crossing from Pueblo to UCAS? It makes sense to me to provide them the map to begin with, and if I then detail the objective to them, they're not going to bother with two border crossings when one is more direct. I could make something up, like the border between Pueblo/UCAS is more heavily guarded or there's no guide for it (since the adventure doesn't give one) but I figured I'd ask you all.