I could easily see one Mafia family getting stuck with a spreading strain of HMHVV. I mean, hell, it's like Herpes. With biting. 
The Mafia. Who is about as Xenophobic as possible?
Who if they have a choice STILL only want Male Humans of Italian/Sicilian Birth in their Ranks?
Who would look at Yomi and go:"That's a good idea, let's do that with some island around italy too!"
And those are now supposed to accept Vampires, who are not even accepted by Metahumans for the most Part?
i'll go to bed now, i'm tired.