I'm a huge fan of
Alchemy redone by Bamce on Reddit. My group and I playtested it for at least three months of regular sessions.
In this new ruleset, we immediately noticed Alchemy was almost entirely a viable alternative to spellcasting. Effectively you pre-prepare spells at the cost of slightly more drain. The removal of potency and the decay of preparations means bookkeeping is significantly reduced and preparations in general have more power behind them because you don't have to worry about Potency screwing you over. You effectively have to write down the force of the preparation and the time you created it, and that's all.
I played an alchemy archer and my favored spells were Petrify, Ignite, Decrease Reaction, and Bugs. The biggest quality of life improvement came with using Edge on the alchemy roll when I used the preparation. If I really needed someone out of the fight, I got to pick if I used edge on the archery test or the Petrify test to either make sure it hit or make sure it petrifies. Either way I thought it ended up pretty balanced, cuz I still needed decent agility.
The one thing we ran into problems with were the Advanced Alchemy rules on page 219 of Street Grimoire. I think my GM wasn't entirely in agreement that everything not labeled 'anchored spells only' should work on preparations, but that's okay.
I'd love if the alchemy rules were made simpler and I love Bamce's, but again I'm not sure if that's in the realm of Errata.