Possibly. Depends on whether they want to go one on one, one on one in sequence, or as a troupe.
If its in sequence, we might be able to each do our primary thing. Isaint can shoot, Tobbis can deck against their decker, SaM can martial arts, Goodnight can sing or duel, and Nitro can use his drone to play cat and mouse. Im not sure of Al's expertise, though I suspect a crafting contest might be something he's good at. Thats hard to do quickly though. A lot of this depends on the harlequins. Im just spitballing.