To address the original post about A dark room and Camouflage.
This example of seeing that someone is present in a dark alley or room is used in
Street Magic, p. 114, Astral Visibility, but the idea of targeting them with a spell is not explicitly called out initially.
but it does go further to say...
Since there are no ranged weapons on the astral plane and spell targeting depends on seeing your target, hiding behind physical shadows works as well as hiding behind a vibrant aura.
For me it IS made clear cut with...
Assencing is the skill of learning information from auras, astral forms and astral signatures.
Not
Astral Shadows in the core RAW (but it is alluded to in
Street Mage by example, as astral shadows can hide a target in the astral).
So, Assencing includes discerning auras, astral forms and astral signatures.
The spell can target anything the caster can physically see or assence...
So, Anything that you can assence you can target.
So for me one would have to find anything in RAW that says Assencing does NOT let you target portions of what you see in the Astral. (Clearly a pure Astral entity or manifestation would require a Mana spell, e.g. no physical spell could target an astral signature). But a Physical spell targeting a samurai in a dark room, easily with a -2 for performing aphysical action via astral sight. But a Mana spell would work with no penalty, unless the Astral Visibility modifiers kicked in (Street Magic, p. 114)
EDIT: FYI - I do not allow touching to qualify for LOS spell targeting. So my hypothetical blind shaman has to astrally perceive (ultimate darkness) to target a git he's holding in his hands.