For an idea of what HMHVV means in Shadowrun, I am going to quote an old post from Mirikon:
Here's the deal, being Infected sucks. For some, it sucks worse than others. Everyone suggesting it isn't a little slice of hell, shut up and sit down. Professor Mirikon's class is in session. Pick up your copy of Running Wild, and read pages 55-64. Then read Street Legends, 90-93. Finally, read Storm Front, pages 139-143. For homework,
Its important to keep in mind that anything infected by HMHVV generally has a bounty on its head, so the player may have to watch his back from his own team... (bounties range from 7500 to 50000. Depending on area, type of infected.)
They really are
monsters. By this I mean they either need
A: meta-human flesh. So they are either hunting metahumans to get it, or making deals with hospitals and chop shops for left overs. (mmm tasty... Ms. Peters breast tumor!), and the diet requirement makes them lousy at dinner parties. (they get ill if they eat anything other then meta-human flesh)
B: Essence. Some infected lose essence at various rates, which means they have to drain it from other sources. (blood is the medium, not the nourishment). Which means, they are in 'essence' draining the very SOULS of their victims. (if you believe that essence = soul...or in souls for that matter). And when essence hits 0, the victim dies. (yes, they can take less then all a person's essence if they choose. But, essence doesn't come back! Once it gone, its gone*)
Lets be clear.. the Infected are not angsty tweens that sparkle in sunlight... They are monsters. And while Runners are not saints, and may be lacking in ethics so badly they give sociopaths a good name, but they generally don't like working with something that considers them "food"
Just saying.
*yes there is a gene therapy that can restore lost essence, but at its availability, cost and time for treatment, it might as not exist for most of the population.