Sixth World Almanac, Corporate Guide, Vice, Stormfront, and Attitude go together well to give you a good overview of the world of the early 2070s.
Clutch of Dragons, Spy Games, Dirty Tricks, War!, and Conspiracy Theories are all interesting looks at different facets of the world, although quality is even more mixed than usual on some of these.
For adventure design, I thought the digital tool set had much better DM advice on building adventures and running campaigns than the core book. One of the books even has five or six adventures and a bit of advice on how to weave them together into a campaign.
I haven't got all the campaign sourcebooks yet; hell, I haven't even read through all the ones I do have. Using them as-is can be a little tough since quite a few are tied into the ongoing soap opera stuff. Plus there are lots of "Elminsters" in these, having exciting adventures while the PCs do guard duty... a few of them do have world info that doesn't appear elsewhere though.