The rule on this particular bioware is very clear as written. I don't see what makes it open for interpretation. If you take two or more boxes of damage, you then reduce the damage by 1. DV is not damage taken, it's damage which needs to be resisted. No offense taken and hopefully you won't find this offensive, either. "Thus lessening the trauma from large wounds and quickly stopping bleeding." If I hit you with a 30 DV attack and you reduce all of the damage by armor, clearly you have not bled or suffered a large wound. That only occurs when you have actually been dealt damage, and that's when Platelet Factories come into play.