At my table I want the players to be able to afford a sustainable medium lifestyle by they time they're 100 karma in.
I classify my missions into 3 levels of difficulty (1-3).
---Level 1 missions (Food Fight, Milk Run, etc) give around 3,000 base. I also allow players to 'loot bodies' without punishment, but organ legging is still frowned upon.
---Level 2 missions (Most convention runs) give around 10,000 base. These missions are lacking crunch most times, in my experience. Lost Islands found, for example, had a great chance to do something but fell flat in the end. Whoops...off topic...
---Level 3 missions (Really dangerous stuff that changes the face of the city/world/campaign) starts at $25,000 base and more than often results in the group getting an additional asset like a vehicle, arms, ware, etc.
Average karma payouts are 5, 8, 10 ... respectively, with bonuses for good RP.
Current group is 27 missions in and just hit 230 karma / $250,000 lifetime totals. It might seem like a lot, but it comes out to about $9300 per job.