Yeah, Nosferatu are humans infected with the Bruckner-Langer variant of HMHVV (Strain 1a). They lose all hair (yes, all), lose a lot of their body-fat (making them very gaunt/emaciated in appearance) and get the stereotypical fangs. Appearance-wise they go straight for Count Orlok but with no explicit pointing of the ears.
All Nosferatu are Awakened as Magicians (no Infected can be Technomancers, that is explicit in Run Faster) and armed with a bunch of powers. Sans Mist Form, Nosferatu gain Compulsion, Fear and Influence over their Vampire cousins, as well as a higher maximum Agility, Willpower, Logic and Intuition. They're by the book faster and smarter than your average metahuman. By the fluff, they also gain a healthy dose of paranoia, hunger for power, sometimes mental illness, etc. Compulsive disorders could explain the legends about vampires being stymied by spreading grain or knotted nets around their graves to keep them busy.
They only lose Essence every four months, and are able to store up to 3 times their natural maximum.
Nosferatu are the second rarest form of Infected in the world; by Patrick Goodman's numbers, there are about 750 Strain 1a Infected in a world of 7.5 billion (one out of every 10 million people, give or take). The only rarer form is the Mutaqua, the Strain 1a Troll; he estimates there to be about 15 of them worldwide, out of that 750.