There is a warning that this topic has not been posted in for at least 120 days. But, I am seeing this for the first time, and wish to retain its context.
In a homebrew game, the players and the GM can get together to discuss die pools beforehand, which all posters here seem to agree is most important. But, in Missions, one not always has control over who the other Runners are at the table.
All too often, it's been my experience that many players are short-sighted as to their character's creation. While it's not that easy to determine where players have wasted Skill Points (if they don't try those skills), it's often easier to infer where they have wasted Metatype, Attributes, Magic, and/or Resources, by what they do (or do not do).
It makes sense that if Skills that were chosen are not used, that those Skill Points have been wasted. But, the same argument could be made that Edge, Attributes, Magic, or Resources expended are underutilized/wasted as well. It all comes down to how one likes to play the game.
I like to do lots of things! That requires lots of Skill Points. Most seem to like to shoot guns and do little else. But, I'm sure that's not true for those who have posted here.
And, wouldn't fewer guns and better Negotiation, First Aid, or Perception make sense? I'll always remember that player with the sniper character who did little or nothing over several Missions.
So, yes! I use Perception much more often than anything else. I believe it's worth 10D plus add-ons. Would I give up Sneaking or Con? No way. Negotiation? Assensing and Magic? No thanks. 2xR4 and 46/10 are nice. I can raise Edge, Attributes, and Resources after a few Runs.