Well, I whoever came up with the horse heads for SR4, I wanted to congratulate for the sheer level of trolling that would entail, intentional or no.
I do have players that are furries, and just seeing their "WTF?" faces when I showed them the pictures in RC. Especially in the wake of the rise of MLP:FiM.
That and the otter-head mermaids.
(then again, changelings are basically actual-furries, but whatever)