Yeah, but you usually don't get that opportunity, especially with a vehicle. Blind-Fire, shooting through an armored vehicle, there are all sorts of penalties. It's even worse if you're using magic of some sort. An AV round into the radiator grille, and so into the engine block, will typically kill the car more easily - or better yet, put the axe to its source of mobility, whether that's a car's much-less-armored tires, the rotors on a helo, prop plane, or boat, or the jet engine on a plane or impeller-driven boat. Almost all of those are vulnerable, and/or less well-armored than the pilot/passenger compartment. Afterwards, you can dispense the people inside at your leisure.
You don't have to kill the vehicle to stop it, you just have to remove its method of propulsion