One I'm working on for my team is the complete psychological destruction of a high profile spokesman. Basically, the team has to slowly drive him insane or otherwise get him to ruin his own image and life. My hacker, mage, rigger, face, and B&E expert are freaking out over the opportunities.
Oh, that's awesome! I like the scientist extraction too. My first run I designed was one where my group had to extract a teen child with magical abilities from an orphanage. Thought about putting a bug hive in it, but decided against it.
One of the best runs I played in was we had to protect a race car driver. She was getting notes about how they were going to kill her if she raced and won again. One of our characters who was about the same size as her decided to play "face off" with her to switch places, and the rest of us were her pit crew. The next race was a multi-nation race from Seattle, to Southern CA, to Denver, and back. It lasted about 5 gaming sessions since "something" came up each part of the race. Meanwhile, we were all investigating who or what was going to do the hit. Awesome stuff.
Another run we had was timed. We had to get an item from a train that only carried upper corp echelon ppl, that moved between destinations in 5 minutes. We had to board the train, take the item unseen, and escape after putting the decoy in it's place before we were found.