For me, skillwires are a great thing for any non-Awakened, non-emerged character who is looking to play extra roles in the party. Not talking the street sammy, they've got too much on their plate already. But a set of skillwires (plus the appropriate skillsofts) can make a Face's job of infiltrating someplace a piece of cake. And there are personafix chips, which sometimes include skillsofts in them. I wouldn't replace core skills for your character with skillsofts (a Face who uses a Con skillsoft is not a Face), but for some less-generally-useful skills that make all the difference when you need them? Yeah. A skillsoft about parachuting, for instance, would be awesome before your HALO insertion, for instance. If a character primarily uses ranged attacks, and is on a run where they screen for weapons, then an Unarmed Combat skillsoft will make a big difference. So I can definitely see a use for them. The problem is the cost of skillsofts is so high. Honestly, I never used them in 4th unless you used either one of the rental services that allowed you to 'borrow' a skillsoft for a couple hours, or some hacked skillsofts that were a fraction of the price, but degraded over time unless you manually patched them. I also liked using personafixes on some of my characters, especially ones with included skillsofts.