I will say that while 3.5 DnD and Pathfinder that grew from it had their own issues, I would really like if Shadowrun got to that level of balanced ease and complexity that kept that tier of edition going. Honestly tho I don't really have suggestions on HOW that might happen, its more a feeling you get as you look over the way stuff is setup.
lore wise, I'm wondering how far away we might be from GitS level 'braincases' and full cyborg bodies, without all the essence issues/cyberzombie stuff. Or the Altered Carbon, 'full bio/etc enhanced sleeve and stacks', something to balance out the 'magic is king' feeling I feel sometimes with the setting.