Out of curiosity, how much karma are they up to at this point? Their numbers are certainly possible, but it takes a little bit of karma to get there.
Some folks above have already posted the run for your life option. That will help against at least one of the AoE's. Other options include:
1). Adjust the Mission's difficulty. Unlike Pathfinder Society, this is permitted in Missions. The following blurb is included in the opening info of every Mission.
Mission Difficulty
Gamemasters are encouraged to use their own judgment, and to adjust the difficulty of the encounter to take into account the abilities of the players. If the players have no magical support, replace magical defenses with mundane ones. If the players are weak on combat, reduce the number of enemies by one or two. Conversely, if they’re steam-rolling the opposition, add one or two enemies to the fight. Missions should be difficult and something of a challenge, but should not be insurmountable.
A simple method for adjusting difficulty is to simply increase the dice pools and Professional Ratings of the enemies. A simple +1 or +2 to all combat and defense tests gives enemies a minor boost in power, while a +3 or 4 will make them truly formidable. Adding to their Professional Rating will give them a larger group Edge pool to draw from, and gamemasters are encourage to use this Edge when logical.
Often a combat scene will tell you if it’s supposed to be challenging or is simply there to serve as filler or a minor obstacle that the players should steamroll through. When possible, use this as a guide to know when to tweak the enemies and encounters. If it doesn’t say, assume the scene should present a challenge to the power levels of the players.
2). Have them spend Edge to go first. Then have two or three of the enemies spend Edge to use suppressive fire to slaughter their dice pools. Multiple uses of suppressive fire will not stack, but doing it two or three times until you have a roll with enough hits is quite effective.
At a certain point, it just becomes hard to challenge characters though. The Chicago Season of Missions has so much content that completing all of it will net you more than 1,000 karma with working for the people. My current PC is a Mystic Adept at 938 karma with 9 Missions left to go. Some of his stupid includes.
- Magic Attribute of 18 (12 natural, 6 power foci)
- Initiate Grade 12 (Centering, Quickening, Power Point x10)
- Drain test of 44 (10 Intuition, 10 Willpower, 12 Centering, 12 Centering Foci)
- Melee defense test 41 (10 Intuition + 10 Reaction + 12 Combat Sense, Adept + 9 Combat Sense, spell)
- Ranged defense test 50 (10 Intuition + 10 Reaction + 12 Combat Sense, Adept + 9 Combat Sense, spell + 9 Deflection, spell)
- Toxin resistance 47 (10 Body + 10 Willpower + 12 Natural Immunity, Adept + 9 Prophylaxis, spell + 6 Chemiscal Resistance)
- Damage resistance test 48 (10 Body + 13 Sleeping Tiger + 4 Argentum Coat + 6 Ballistic Shield + 2 Ballistic Mask + 1 Forearm Guards + 3 Mystic Armor, Adept + 9 Armor, Spell)
- Adept Spell Resistance at 12
- Initiative 5d6+29
His offensive capability is good, but not especially impressive since I didn't specialize in it (24 spellcasting dice, 16 punching dice). Most of the people I play with are in the 250-350 karma range, so it's tough for the GMs to adjust to my scale without butchering the others. Because of that I generally contribute to combat by buffing and sustaining a bunch of spells for the other characters so they don't have to try.