Hiya gang! I want to start running a Shadowrun game. Sounds simple enough, right? Except I'm completely new to Shadowrun and am pretty out of touch with table top role playing these days. Sorry for the ramble, but I want to give a little background for how I ended up here

I used to role play a lot, at least weekly if not more often. That was 15+ years ago which is really depressing. Denial of age aside, I used to both play and GM. Started with AD&D like many people, moved on to the whole World of Darkness bit from White Wolf (Vampire, Werewolf, Mage, etc.) then ended up in a tight-nit group focused entirely on story and character interaction with light doses of dice once in a while based on a smattering of rules we cobbled together from various game systems. We actually have a Shadowrun 2nd edition core book from back in our gaming hayday in near-mint condition that we've never really used!
Fast-forward to the here and now. I've been jonesing for some pen and paper role playing for a while and recently a friend ran a small Cyberpunk2020 game for my wife and I. So, 2 players and a GM. It was a lot of fun and I want to go further with it all. Then there's the recent Shadowrun kickstarter which I donated to and it really got me thinking about Shadowrun. I love the mix of cyberpunk + magic + a dash of fantasy turned on it's ear.
So I'm reading up on Shadowrun, getting a handle on the setting, the culture, the way the world works. I'll probably get the current core book and the Runner's Toolkit and stick with that for a while.
My questions, if you've managed to stay with me this long, are:
* How many players do you feel are necessary for a solid campaign?
* How many players can you replace with NPCs sprinkled into the story when needed? Don't worry - not as "GM Player Characters"

* Single Player a) How hard is it in Shadowrun to GM a game for a single player?
* Single Player b) Which archetypes are more or less fitting for a single player session/campaign?
There aren't many people I know that both want to game *and* have schedules that mesh well with mine. My wife and I both want to game and so I was thinking of running some single-player sessions just for her to get us used to the mechanics and to just plain have fun so we're not sitting around waiting on friends to find time to join us. Is this feasable? Any suggestions?
Thanks everyone! I'm really looking forward to some Shadowrun!
~ Shadowplay ~
p.s. - my forum name is purely coincidence as I've used it off and on for a long time, but seems fitting here
