Well, no worse a time than if you were a mage. Remember, this is a world where they've been hit with magic, dragons, two matrix crashes, three rounds of VITAS, SURGE, HMHVV, a dragon running for president and then getting blown up, dragons on the boards of megacorps... I could go on, but you get the idea. A lot of strange has been thrown at the world, and people have gotten a bit jaded. MCT spun the TM crisis hard to whip up fear, but Horizon is better at spin than MCT by far. The world had about a year of major freakout, and then people came to their senses. There are still people who rabidly hate technomancers, but for most people, as long as they aren't doing anything to them, they have more immediate problems, such as taking care of those TPS reports that the boss wants done in two hours, and so on.
A good example would be the earthquake in Haiti a couple years ago (RL, not SR). For a couple months, it was all everyone could talk about, and then people moved on to the next thing to take their attention. TMs were a big thing, and every so often someone will haul them out to make a point (just like they do with mages and shadowrunners), but they're here now, and not going away, so most people went back to concentrating on their own life.
Now, in the shadows, it is a different set of challenges, but the same rule applies. There are people in the shadows who fear TMs (Clockwork is a good example), just like there are people in the shadows who fear mages, or disdain anyone walking the razor's edge of cyberware, or can't stand hackers. But for the most part, biz is biz, and at the end of the day, people look to do what is best for their bottom line.