Agreed that 30 Nights is an odd campaign. Also agree that I would not start off with it, with the expectation that it is normal shadowrun.
My personal take is that 30 Nights is easiest to play with "not-shadowrunners". That is, a lot of shadowrunners are quite mercenary, very capable, and without deep roots in their community. So really the sane response of a lot of shadowrunners would be to either a) start hiking out of town, or b) bunker up and start looting everything they can. On the other hand if you have some moderately capable people who are maybe a little shady, but not really professional shadowrunners yet, who happen to get caught in that situation, by the end of it they might be pulled a fair way into the shadows. (one tip, do a mission-zero which takes the player characters well out of the core of the city, where their electronics won't be fried, but give them good reason to head back to the heart of things. Like run the fan created adventure "The Delian Data Tombs", placing the data tombs up in Markham, and they are persuaded to do this as a favor for a friend, the black-out hits just after they finish the job, but they need to find the friend to get paid for their work, pulling them back into the heart of things).
Having one of the NPC from 30 Nights send them to Barcelona for Assassin's Night would work well.
If you want to do it the other way around that is fine, but maybe consider compressing 30 Nights somewhat, and add a good reason for them to stick around in the dark and do some 'hooding' (shadowrun term for when runners do something mostly to help the community, as opposed to for personal gain).