OTOH, SR has never been a "Universal Simulator" kind of game, and 6WE is not attempting to be one either. In 6WE, you play a Shadowrunner. You get in fights with people like gangers, mob soldiers, cops, and security guards. 50 year old out of shape former little-leaguers aren't part of the calculus (for the combat system, at least).
It doesn't matter if someone like "real world us" lacks the physical strength to replicate the damage someone like a Mark McGuire could do with a baseball bat. In the RPG, the presumption is if a PC or NPC lacks raw power, they instead make up for it with speed and quickness. The presumption is if you're employing a melee weapon, then you know HOW to employ the melee weapon to maximum effectiveness given your own physical capabilities.
Yes this kind of breaks down if your PC is in fact a 50 year old out of shape person with terrible physical stats across the board. There are valid archetypes you could be going for where that'd fit, and of course you might find such a PC stuck fighting a professional combatant like a ganger, mob soldier, etc. But you won't find that happening often, not unless you're an idiot of a player who refuses to keep a clearly non-combatant kind of runner out of close combat. Anyway, the point I want to make on this contingency is rules don't inherently need to address exceptions to the norm. "Ok, your runner lacks a Juicer's Strength? And simultaneously also lacks a Ninja's agility? Fine, your DV is penalized." Or, if you're reluctant to impose non-explicitly stated penalties (i.e. "house rules") you can work within what's explicitly provided and decree that a fat, out of shape would-be-melee-combatant just automatically is giving away circumstantial edge to everyone he swings at.
