...hmm, in the latest release, Section 26, "Better Than Bad", bottom of page 75, it mentions that Karma can be used to increase a personal (not Mission Specific) contact's loyalty and connection referencing p. 164 of the supplement.
RPG mechanics exist to give structure and consistency to the game world, true, but at the end of the day, you’re fighting dragons with algebra and random number generators.
...yeah I don't have the book yet so not sure how it actually reads. I though I heard that one could use Karma to purchase and build up a new contact.