If I were GM and allowed both qualities on one character, I'd rule that Called Shot happens before Strive for Perfection. So the basic Called shots would be reduced down to -1 dice (4 base penalty -2 for Sharpshooter = 2 penalty/2 = 1 penalty) instead of no penalty. So now your Eye called shot would be -4 dice (10 base penalty -2 for Sharpshooter = 8 penalty/2 for Strive for Perfection = 4 penalty) with both. Still really good, but not completely broken.
I literally can't make a character without Sharpshooter. For 4 Karma it's just good. Whereas Strive for Perfection seems overpriced compared to Sharpshooter. The only time it really makes a difference is the specific body hit locations that are -8+ dice. Eye Called shot is -8 dice with Sharpshooter, but -5 with Strive for Perfection. 3 dice still isn't worth the cost to me when you can choose other called shot options with a lower penalty.
More Sharpshooter fawning... let's say we're running with 18 dice with Automatics before everything kicks in. NON-Called Shots with all RANGED weapons are at -1 dice. All ranged called shots are at a -2 dice now though, using your base 18 dice. So a Vitals Called shot is now rolling with 16 dice for +2 DV and your normal shots are at 17 dice. Considering you added +2 DV which will require an average of 6 more soak dice for them to cover, I think it's worth it. Plus you can do things like:
With Sharpshooter
(-2 dice) Shake up + Stick n Shock rounds = Opponent loses 10 initiative
(-2 dice) Harder knock + Gel rounds = You don't have to carry normal ammo anymore, just hit em where it hurts with Gel
(-2 dice) Vitals + Any rounds = +2 DV
(-2 dice) Bulls-Eye Double Tap/Burst + APDS rounds + Gun with -2 base AP and SA/burst = 10 AP burst
(-2 dice) Shredded Flesh + Flechette round = Target bleeds out over time
I'm having a lot of fun with:
Ares Alpha (11P v -2AP) + Flechette (+2DV +5AP) + Vitals (+2DV) + Aimed Burst (+1DV) = 16P v+3AP You can also use Enhanced Suppression and it tears up pretty good.
Makes me think of this:
https://www.youtube.com/watch?v=OzliqFzK36E