I really like the new Prototype Transhuman quality, but ...
I'm having trouble justifying it in *any* build.
10 karma for ignoring 1 essence of bioware seems great on the surface, but the opportunity cost is that you need to put in the nuyen for 1 karma of bioware.
Realistically you need priority C resources to get some nice bioware to make the quality worth it. But the opportunity cost there is often either a priority worth of attributes (4 points), or a priority worth of special attributes (3 points of edge or whatever), or a substantial amount of skillpoints.
I've tried it with adept, technomancer, mystic adept, magician ... I just can't seem to make it ever 'worth it'.
Any thoughts?