Target: Wastelands (Third Edition).
I'd say the adventure book has more likelihood of being released given the current slate of books being produced. Given the relative lack of popularity for location books that has always been an issue with Shadowrun, it makes sense that if CGL does pursue this venture (and I hope they will. Maybe I'll propose the book, but right now I'm working on another book idea) it will be similar to how they are incorporating genre/style/background material, rules, storyline, and new (or long-ignored) settings that are especially tailored to a specific idea. A space book would be able to deal with Earth-based locations (launch facilities, the base of the space elevator, etc.) and cover orbitals in general. So, yes, a spacerunning book is possible. There are other considerations, and frankly it would be a while given what's already in production and planning.
Granted, there is enough material and potential that specific (and I'll be honest, cheaper) ebooks could follow suit. I mean ... I have a very basic proposal right now for a 30,000 word ebook supplement for an upcoming book. Although I'm not sure how this works because the ebooks are a separate thing, related but not ... They have their own purpose and own set of goals (which is why they have their own line developer).